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What a mistake that had been, to create a construct [AI] that could suffer. He knew that now. Life, pain, death, they were no playthings. Biology was serious business, not for amateurs and foolish gods.
David Marusek Mind Over Ship
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What a mistake that had been, to create a construct [AI] that could suffer. He knew that now. Life, pain, death, they were no playthings. Biology was serious business, not for amateurs and foolish gods.

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When General Genius built the first mentar [Artificial Intelligence] mind in the last half of the twenty-first century, it based its design on the only proven conscious material then known, namely, our brains. Specifically, the complex structure of our synaptic network. Scientists substituted an electrochemical substrate for our slower, messier biological one. Our brains are an evolutionary hodgepodge of newer structures built on top of more ancient ones, a jury-rigged system that has gotten us this far, despite its inefficiency, but was crying out for a top-to-bottom overhaul.Or so the General genius engineers presumed. One of their chief goals was to make minds as portable as possible, to be easily transferred, stored, and active in multiple media: electronic, chemical, photonic, you name it. Thus there didn't seem to be a need for a mentar body, only for interchangeable containers. They designed the mentar mind to be as fungible as a bank transfer.And so they eliminated our most ancient brain structures for regulating metabolic functions, and they adapted our sensory/motor networks to the control of peripherals.As it turns out, intelligence is not limited to neural networks, Merrill. Indeed, half of human intelligence resides in our bodies outside our skulls. This was intelligence the mentars never inherited from us....The genius of the irrational......We gave them only rational functions -- the ability to think and feel, but no irrational functions... Have you ever been in a tight situation where you relied on your 'gut instinct'? This is the body's intelligence, not the mind's. Every living cell possesses it. The mentar substrate has no indomitable will to survive, but ours does.Likewise, mentars have no 'fire in the belly,' but we do. They don't experience pure avarice or greed or pride. They're not very curious, or playful, or proud. They lack a sense of wonder and spirit of adventure. They have little initiative. Granted, their cognition is miraculous, but their personalities are rather pedantic.But probably their chief shortcoming is the lack of intuition. Of all the irrational faculties, intuition in the most powerful. Some say intuition transcends space-time. Have you ever heard of a mentar having a lucky hunch? They can bring incredible amounts of cognitive and computational power to bear on a seemingly intractable problem, only to see a dumb human with a lucky hunch walk away with the prize every time. Then there's luck itself. Some people have it, most don't, and no mentar does.So this makes them want our bodies...Our bodies, ape bodies, dog bodies, jellyfish bodies. They've tried them all. Every cell knows some neat tricks or survival, but the problem with cellular knowledge is that it's not at all fungible; nor are our memories. We're pretty much trapped in our containers.

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Suddenly I realized that a cell's life is controlled by the physical and energetic environment and not by its genes. Genes are simply molecular blueprints used in the construction of cells, tissues, and organs. The environment serves as a "contractor" who reads and engages those genetic blueprints and is ultimately responsible for the character of a cell's life. It is a single cell's "awareness" of the environment, not its genes, that sets into motion the mechanisms of life.

BL
Bruce H. Lipton

The Biology of Belief: Unleashing the Power of Consciousness, Matter and Miracles

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And perhaps there is none, no morrow anymore, for one who has waited so long for it in vain. And perhaps he has come to that stage of his instant when to live is to wander the last of the living in the depths of an instant without bounds, where the light never changes and the wrecks all look alike. Bluer scarcely than white of egg the eyes stare into the space before them, namely the fullness of the great deep and unchanging calm. But at long intervals they close, with the gentle suddenness of flesh that tightens, often without anger, and closes on itself.