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neo-darwinism

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I recently asked more than seventy eminent researchers if they would have done I their work differently if they had thought Darwin's theory was wrong. The responses were all the same: no. I also examined the outstanding biodiscoveries of the past century: the discovery of the double helix; the characterization of the ribosome: the mapping of genomes; research on medications and drug reactions: improvements in food production and sanitation; the development of new surgeries; and others. I even queried biologists working in areas where one would expect the Darwinian paradigm to have most benefited research, such as the emergence of resistance to antibiotics and pesticides. Here, as elsewhere, I found that Darwin's theory had provided no discernible guidance, but was brought in, after the breakthroughs, as an interesting narrative gloss.

PS
Philip S. Skell

Why do we invoke Darwin? Evolutionary theory contributes little to experimental biology

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In science's pecking order, evolutionary biology lurks somewhere near the bottom, far closer to phrenology than to physics. For evolutionary biology is a historical science, laden with history's inevitable imponderables. We evolutionary biologists cannot generate a Cretaceous Park to observe exactly what killed the dinosaurs; and, unlike "harder" scientists, we usually cannot resolve issues with a simple experiment, such as adding tube A to tube B and noting the color of the mixture.

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For those scientists who take it seriously, Darwinian evolution has functioned more as a philosophical belief system than as a testable scientific hypothesis. This quasi-religious function of the theory is, I think, what lies behind many of the extreme statements that you have doubtless encountered from some scientists opposing any critical analysis of neo-Darwinism in the classroom. It is also why many scientists make public statements about the theory that they would not defend privately to other scientists like me.

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To suppose that the eye with all its inimitable contrivances for adjusting the focus to different distances, for admitting different amounts of light, and for the correction of spherical and chromatic aberration, could have been formed by natural selection, seems, I confess, absurd in the highest degree...The difficulty of believing that a perfect and complex eye could be formed by natural selection , though insuperable by our imagination, should not be considered subversive of the theory.

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No fossil is buried with its birth certificate. That, and the scarcity of fossils, means that it is effectively impossible to link fossils into chains of cause and effect in any valid way... To take a line of fossils and claim that they represent a lineage is not a scientific hypothesis that can be tested, but an assertion that carries the same validity as a bedtime story__musing, perhaps even instructive, but not scientific.

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Life is so diversified that to any statement I could make about living organisms there are exceptions. Because of the many exceptions, I should qualify everything I say with hedging phrases such as 'generally,' 'usually,' and 'almost always' But I'm afraid the constant repetition of these hedges will slow me down and bore you. So let's make a pact now that I forego the hedging phrases and you are to understand that almost all my statements may have rare exceptions.

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I am suggesting here that organisms have a built-I capability of adapting to their environment. I am suggesting that to the extent that evolution occurs, it occurs at the level of the organism. This suggestion differs sharply from the thesis of the NDT, which holds that evolution occurs only at the level of the population. Organisms contain within themselves the information that enables them to develop a phenotype adaptive to a variety of environments. The adaptation can occur by a change in the genome through a genetic change triggered by the environment, or it can occur without any genetic change.