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The Buddha taught that all life is suffering. We might also say that life, being both attractive and constantly dangerous, is intoxicating and ultimately toxic. 'Toxic' comes from toxicon, Pendell tells us, with a root meaning of 'a poisoned arrow.' All organic life is struck by the arrows of real and psychic poisons. This is understood by any true, that is to say, not self-deluding, spiritual path.

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Gary Snyder

Pharmako/Poeia: Plant Powers, Poisons, and Herbcraft

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The movement of descent and discovery begins at the moment you consciously become dissatisfied with life. Contrary to most professional opinion, this gnawing dissatisfaction with life is not a sign of "mental illness," nor an indication of poor social adjustment, nor a character disorder. For concealed within this basic unhappiness with life and existence is the embryo of a growing intelligence, a special intelligence usually buried under the immense weight of social shams. A person who is beginning to sense the suffering of life is, at the same time, beginning to awaken to deeper realities, truer realities. For suffering smashes to pieces the complacency of our normal fictions about reality, and forces us to become alive in a special sense__o see carefully, to feel deeply, to touch ourselves and our worlds in ways we have heretofore avoided. It has been said, and truly I think, that suffering is the first grace. In a special sense, suffering is almost a time of rejoicing, for it marks the birth of creative insight. But only in a special sense. Some people cling to their suffering as a mother to its child, carrying it as a burden they dare not set down. They do not face suffering with awareness, but rather clutch at their suffering, secretly transfixed with the spasms of martyrdom. Suffering should neither be denied awareness, avoided, despised, not glorified, clung to, dramatized. The emergence of suffering is not so much good as it is a good sign, an indication that one is starting to realize that life lived outside unity consciousness is ultimately painful, distressing, and sorrowful. The life of boundaries is a life of battles__f fear, anxiety, pain, and finally death. It is only through all manner of numbing compensations, distractions, and enchantments that we agree not to question our illusory boundaries, the root cause of the endless wheel of agony. But sooner or later, if we are not rendered totally insensitive, our defensive compensations begin to fail their soothing and concealing purpose. As a consequence, we begin to suffer in one way or another, because our awareness is finally directed toward the conflict-ridden nature of our false boundaries and the fragmented life supported by them.

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Ken Wilber

No Boundary: Eastern and Western Approaches to Personal Growth

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Followers of Jesus stake their claim on the firm belief that God will one day heal the planet of pain and death. Until that day arrives, the case against God must rely on incomplete evidence. We cannot really reconcile our pain-wracked world with a loving God because what we experience now is not the same as what God intends. Jesus himself prayed that God's will "be done, on earth as it is in heaven," a prayer that will not be fully answered until evil and suffering are finally defeated.

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Philip Yancey

The Question That Never Goes Away